Structural and functional characterization of flavylium salts interaction with endogenous biological targets

Línea de investigación

Protein Structure and Function.

Descripción

Anthocyanins are a subgroup of flavonoids responsible for most red and blue colors found in flowers and fruits. Although usually represented by the flavylium cation form, these species are only stable at very acidic pH values leading to the reversible formation of other species at higher pH values. The composition of the final equilibrium strongly depends on the nature and position of the substituents decorating the flavylium core and on medium conditions such as pH, temperature, polarity, etc. This study aims to better understand the molecular mechanism of the interaction between flavylium salts with molecule targets in cells in order to better comprehend their potential pharmacological role o in disease for future use of anthocyanins as therapeutical drugs.

Contacto

Alejandro Samhan Arias.

Correo electrónico: alejandro.samhan@uam.es.