Facultad de Ciencias

• Regulation of stem cell differentiation during developmental processes.
• Nonlinear regulation in pathways and its impact on disease treatment.
• Stochasticity and effect of perturbations in biological networks.

1. Novel role for the midbody in primary ciliogenesis by polarized epithelial cells, M. Bernabé-Rubio, G. Andrés, J. Casares-Arias, J. Fernández-Barrera, L. Rangel, N. Reglero-Real, D. C. Gershlick, J. J. Fernández, J. Millán, I. Correas, D. G. Miguez, M. A. Alonso, J. Cell Biology, 214, pp 259–273, (2016). [URL]

2. Myosin light-chain phosphatase regulates basal actomyosin oscillations during morphogenesis, A. Valencia-Expósito, I. Grosheva, D. G. Míguez, A. González-Reyes, M. D. Martín-Bermudo, Nature Communications 7, 10746, (2016). [URL]

3. A Branching Process to Characterize the Dynamics of Stem Cell Differentiation, D. G. Míguez, Scientific Reports, 5, 13265 (2015). [URL]

4. A Tunable Coarse-Grained Model for Ligand-Receptor Interaction, T. Ruiz-Herrero, J. Estrada, R. Guantes, D. G. Miguez, PLOS Computational Biology, 9, e1003274, (2013). [URL]

5. Smad2 and Smad3 cooperate and antagonize simultaneously in vertebrate neurogenesis, David G. Míguez, Estel Gil-Guiñón, Sebastián Pons, Elisa Martí, J Cell Sci, 126, 5335, (2013). [URL]

6. Sonic Hedgehog Signaling Switches the Mode of Division in the Developing Nervous System, M. Saade, I. Gutiérrez-Vallejo, G. Le Dréau, M. A. Rabadán, D. G. Miguez, J. Buceta, E. Martí,Cell Reports, 4, pp 492–503, (2013). [URL]

7. Intron length increases oscillatory periods of gene expression in animal cells, Ian A. Swinburne, David G. Miguez, Dirk Landgraf, and Pamela A. Silver, Genes & Dev., 22, pp 2342-2346, (2008). [URL]

8. Fronts and pulses in an enzymatic reaction catalyzed by glucose oxidase, D. G. Míguez, V. K. Vanag, I. R. Epstein, P.N.A.S., 104, 6992, (2007). [URL]

ID de investigador / Código ORCID 

- orcid.org/0000-0001-8065-1142