Facultad de Ciencias

Enantioselective H-Bond-Directing Approach for Trienamine-mediated Reactions in Asymmetric Synthesis

Autor/es

Albrecht, Ł; Cruz Acosta, F.; Fraile, A.; Albrecht, A.; Christensen, J.; Jørgensen, K. A.

Año de edición

2012

Referencia completa

Angew. Chem. Int. Ed. 2012, 51, 9088-9092. DOI: 10.1002/anie.201204790

Resumen

Right direction: The presented enantioselective strategy for the preparation of diversely functionalized tetrahydroxanthones is based on a trienamine‐mediated cycloaddition between 2,4‐dieneals and activated chromones. It is possibile to control the stereochemical outcome of such reactions by employing an H‐bond‐directing aminocatalyst.

Otros datos de interés

Destacada por Synfacts 2012, 8, 1257